Dynamics of SARS-CoV-2 Antibody Response to CoronaVac followed by Booster Dose of BNT162b2 Vaccine

We evaluated the longitudinal dynamics of antibody response to the SARS-CoV-2 vaccine CoronaVac and the effect of a booster dose of BNT162b2 vaccine. We found a robust antibody response after the second dose of CoronaVac that wanes over time. The response was recovered by BNT162b2, which boosted ant...

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Detalles Bibliográficos
Autores principales: Fonseca, Marcela Helena Gambim, Pinto, Ana Carolina Matias Dinelly, Silva, Maria Francilene Souza, de Melo, Amanda Campelo Lima, Vasconcelos, Germana Silva, dos Santos, Eduardo Ruback, de Carvalho Araújo, Fernanda Montenegro, de Andrade, Luiz Odorico Monteiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2022
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9155880/
https://www.ncbi.nlm.nih.gov/pubmed/35421324
http://dx.doi.org/10.3201/eid2806.220061
Descripción
Sumario:We evaluated the longitudinal dynamics of antibody response to the SARS-CoV-2 vaccine CoronaVac and the effect of a booster dose of BNT162b2 vaccine. We found a robust antibody response after the second dose of CoronaVac that wanes over time. The response was recovered by BNT162b2, which boosted anti-spike antibody titers.

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