Dynamics of SARS-CoV-2 Antibody Response to CoronaVac followed by Booster Dose of BNT162b2 Vaccine

We evaluated the longitudinal dynamics of antibody response to the SARS-CoV-2 vaccine CoronaVac and the effect of a booster dose of BNT162b2 vaccine. We found a robust antibody response after the second dose of CoronaVac that wanes over time. The response was recovered by BNT162b2, which boosted ant...

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Autores principales: Fonseca, Marcela Helena Gambim, Pinto, Ana Carolina Matias Dinelly, Silva, Maria Francilene Souza, de Melo, Amanda Campelo Lima, Vasconcelos, Germana Silva, dos Santos, Eduardo Ruback, de Carvalho Araújo, Fernanda Montenegro, de Andrade, Luiz Odorico Monteiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2022
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9155880/
https://www.ncbi.nlm.nih.gov/pubmed/35421324
http://dx.doi.org/10.3201/eid2806.220061
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author Fonseca, Marcela Helena Gambim
Pinto, Ana Carolina Matias Dinelly
Silva, Maria Francilene Souza
de Melo, Amanda Campelo Lima
Vasconcelos, Germana Silva
dos Santos, Eduardo Ruback
de Carvalho Araújo, Fernanda Montenegro
de Andrade, Luiz Odorico Monteiro
author_facet Fonseca, Marcela Helena Gambim
Pinto, Ana Carolina Matias Dinelly
Silva, Maria Francilene Souza
de Melo, Amanda Campelo Lima
Vasconcelos, Germana Silva
dos Santos, Eduardo Ruback
de Carvalho Araújo, Fernanda Montenegro
de Andrade, Luiz Odorico Monteiro
author_sort Fonseca, Marcela Helena Gambim
collection PubMed
description We evaluated the longitudinal dynamics of antibody response to the SARS-CoV-2 vaccine CoronaVac and the effect of a booster dose of BNT162b2 vaccine. We found a robust antibody response after the second dose of CoronaVac that wanes over time. The response was recovered by BNT162b2, which boosted anti-spike antibody titers.
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spelling pubmed-91558802022-06-04 Dynamics of SARS-CoV-2 Antibody Response to CoronaVac followed by Booster Dose of BNT162b2 Vaccine Fonseca, Marcela Helena Gambim Pinto, Ana Carolina Matias Dinelly Silva, Maria Francilene Souza de Melo, Amanda Campelo Lima Vasconcelos, Germana Silva dos Santos, Eduardo Ruback de Carvalho Araújo, Fernanda Montenegro de Andrade, Luiz Odorico Monteiro Emerg Infect Dis Dispatch We evaluated the longitudinal dynamics of antibody response to the SARS-CoV-2 vaccine CoronaVac and the effect of a booster dose of BNT162b2 vaccine. We found a robust antibody response after the second dose of CoronaVac that wanes over time. The response was recovered by BNT162b2, which boosted anti-spike antibody titers. Centers for Disease Control and Prevention 2022-06 /pmc/articles/PMC9155880/ /pubmed/35421324 http://dx.doi.org/10.3201/eid2806.220061 Text en https://creativecommons.org/licenses/by/4.0/Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Fonseca, Marcela Helena Gambim
Pinto, Ana Carolina Matias Dinelly
Silva, Maria Francilene Souza
de Melo, Amanda Campelo Lima
Vasconcelos, Germana Silva
dos Santos, Eduardo Ruback
de Carvalho Araújo, Fernanda Montenegro
de Andrade, Luiz Odorico Monteiro
Dynamics of SARS-CoV-2 Antibody Response to CoronaVac followed by Booster Dose of BNT162b2 Vaccine
title Dynamics of SARS-CoV-2 Antibody Response to CoronaVac followed by Booster Dose of BNT162b2 Vaccine
title_full Dynamics of SARS-CoV-2 Antibody Response to CoronaVac followed by Booster Dose of BNT162b2 Vaccine
title_fullStr Dynamics of SARS-CoV-2 Antibody Response to CoronaVac followed by Booster Dose of BNT162b2 Vaccine
title_full_unstemmed Dynamics of SARS-CoV-2 Antibody Response to CoronaVac followed by Booster Dose of BNT162b2 Vaccine
title_short Dynamics of SARS-CoV-2 Antibody Response to CoronaVac followed by Booster Dose of BNT162b2 Vaccine
title_sort dynamics of sars-cov-2 antibody response to coronavac followed by booster dose of bnt162b2 vaccine
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9155880/
https://www.ncbi.nlm.nih.gov/pubmed/35421324
http://dx.doi.org/10.3201/eid2806.220061
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