Serum Neutralization of SARS-CoV-2 Omicron BA.1 and BA.2 after BNT162b2 Booster Vaccination

The SARS-CoV-2 Omicron variant BA.2 sublineage is rapidly replacing earlier Omicron lineages, suggesting BA.2 has increased vaccine evasion properties. We measured neutralization titers of authentic BA.1 and BA.2 isolates in serum samples from persons who received the BNT162b2 booster vaccine. All s...

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Autores principales: Pedersen, Rune M., Bang, Line L., Madsen, Lone W., Sydenham, Thomas V., Johansen, Isik S., Jensen, Thøger G., Justesen, Ulrik S., Andersen, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2022
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9155893/
https://www.ncbi.nlm.nih.gov/pubmed/35356875
http://dx.doi.org/10.3201/eid2806.220503
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author Pedersen, Rune M.
Bang, Line L.
Madsen, Lone W.
Sydenham, Thomas V.
Johansen, Isik S.
Jensen, Thøger G.
Justesen, Ulrik S.
Andersen, Thomas E.
author_facet Pedersen, Rune M.
Bang, Line L.
Madsen, Lone W.
Sydenham, Thomas V.
Johansen, Isik S.
Jensen, Thøger G.
Justesen, Ulrik S.
Andersen, Thomas E.
author_sort Pedersen, Rune M.
collection PubMed
description The SARS-CoV-2 Omicron variant BA.2 sublineage is rapidly replacing earlier Omicron lineages, suggesting BA.2 has increased vaccine evasion properties. We measured neutralization titers of authentic BA.1 and BA.2 isolates in serum samples from persons who received the BNT162b2 booster vaccine. All samples neutralized BA.1 and BA.2 at equal median values.
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spelling pubmed-91558932022-06-04 Serum Neutralization of SARS-CoV-2 Omicron BA.1 and BA.2 after BNT162b2 Booster Vaccination Pedersen, Rune M. Bang, Line L. Madsen, Lone W. Sydenham, Thomas V. Johansen, Isik S. Jensen, Thøger G. Justesen, Ulrik S. Andersen, Thomas E. Emerg Infect Dis Research Letter The SARS-CoV-2 Omicron variant BA.2 sublineage is rapidly replacing earlier Omicron lineages, suggesting BA.2 has increased vaccine evasion properties. We measured neutralization titers of authentic BA.1 and BA.2 isolates in serum samples from persons who received the BNT162b2 booster vaccine. All samples neutralized BA.1 and BA.2 at equal median values. Centers for Disease Control and Prevention 2022-06 /pmc/articles/PMC9155893/ /pubmed/35356875 http://dx.doi.org/10.3201/eid2806.220503 Text en https://creativecommons.org/licenses/by/4.0/Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Pedersen, Rune M.
Bang, Line L.
Madsen, Lone W.
Sydenham, Thomas V.
Johansen, Isik S.
Jensen, Thøger G.
Justesen, Ulrik S.
Andersen, Thomas E.
Serum Neutralization of SARS-CoV-2 Omicron BA.1 and BA.2 after BNT162b2 Booster Vaccination
title Serum Neutralization of SARS-CoV-2 Omicron BA.1 and BA.2 after BNT162b2 Booster Vaccination
title_full Serum Neutralization of SARS-CoV-2 Omicron BA.1 and BA.2 after BNT162b2 Booster Vaccination
title_fullStr Serum Neutralization of SARS-CoV-2 Omicron BA.1 and BA.2 after BNT162b2 Booster Vaccination
title_full_unstemmed Serum Neutralization of SARS-CoV-2 Omicron BA.1 and BA.2 after BNT162b2 Booster Vaccination
title_short Serum Neutralization of SARS-CoV-2 Omicron BA.1 and BA.2 after BNT162b2 Booster Vaccination
title_sort serum neutralization of sars-cov-2 omicron ba.1 and ba.2 after bnt162b2 booster vaccination
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9155893/
https://www.ncbi.nlm.nih.gov/pubmed/35356875
http://dx.doi.org/10.3201/eid2806.220503
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