Cargando…

MAP9 Exhibits Protumor Activities and Immune Escape toward Bladder Cancer by Mediating TGF-β1 Pathway

To investigate more potential targets for the treatment of human bladder cancer, quantitative reverse transcription polymerase chain reaction (qRT-PCR) and high-content screening (HCS) analysis were performed, and microtubule-associated protein 9 (MAP9), which had the strongest proliferation inhibit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Chong, Han, Bing, Guo, Yuanyuan, Guan, Han, Chen, Zhijun, Liu, Beibei, Sun, Wenyan, Li, Wenyong, Sun, Wei, Wang, Sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9155934/ https://www.ncbi.nlm.nih.gov/pubmed/35656338 http://dx.doi.org/10.1155/2022/3778623

Ejemplares similares

Protumor immunity and breast cancer development
por: Coussens, LM
Publicado: (2009)

High mammographic density in women is associated with protumor inflammation
por: Huo, Cecilia W., et al.
Publicado: (2018)

Regulation and Functions of Protumoral Unconventional T Cells in Solid Tumors
por: Barsac, Emilie, et al.
Publicado: (2021)

Tumor-Associated Macrophages: Protumoral Macrophages in Inflammatory Tumor Microenvironment
por: Malekghasemi, Somaiyeh, et al.
Publicado: (2020)

Plasma Fibrinogen Predicts the Prognosis of Bladder Cancer Patients After Radical Cystectomy
por: Yang, Shuai, et al.
Publicado: (2020)

Evidence that cervical cancer cells cultured as tumorspheres maintain high CD73 expression and increase their protumor characteristics through TGF‐β production
por: García‐Rocha, Rosario, et al.
Publicado: (2022)

Monocyte Differentiation towards Protumor Activity Does Not Correlate with M1 or M2 Phenotypes
por: Chimal-Ramírez, G. Karina, et al.
Publicado: (2016)

An acid trip activates protumoral macrophages to promote hepatocellular carcinoma malignancy
por: Graham, Nicola, et al.
Publicado: (2022)

Involvement of protumor macrophages in breast cancer progression and characterization of macrophage phenotypes
por: Komohara, Yoshihiro, et al.
Publicado: (2023)

Protumoral roles of melanoma inhibitory activity 2 in oral squamous cell carcinoma
por: Kurihara, M, et al.
Publicado: (2013)

Protumor Activities of the Immune Response: Insights in the Mechanisms of Immunological Shift, Oncotraining, and Oncopromotion
por: Chimal-Ramírez, G. K., et al.
Publicado: (2013)

Targeting the Tumor Microenvironment: The Protumor Effects of IL-17 Related to Cancer Type
por: Fabre, Joseph, et al.
Publicado: (2016)

Estrogen reprograms the activity of neutrophils to foster protumoral microenvironment during mammary involution
por: Chung, Hwa Hwa, et al.
Publicado: (2017)

Enhanced lipid biosynthesis in human tumor-induced macrophages contributes to their protumoral characteristics
por: Rabold, Katrin, et al.
Publicado: (2020)

Extracellular vesicles shed from gastric cancer mediate protumor macrophage differentiation
por: Ito, Atene, et al.
Publicado: (2021)

N‐acetylaspartate release by glutaminolytic ovarian cancer cells sustains protumoral macrophages
por: Menga, Alessio, et al.
Publicado: (2021)

Basal Cell Carcinoma in Gorlin’s Patients: a Matter of Fibroblasts-Led Protumoral Microenvironment?
por: Gache, Yannick, et al.
Publicado: (2015)

Cancer-associated fibroblasts promote an immunosuppressive microenvironment through the induction and accumulation of protumoral macrophages
por: Takahashi, Hideyuki, et al.
Publicado: (2016)

XBP1 regulates the protumoral function of tumor-associated macrophages in human colorectal cancer
por: Zhao, Yahui, et al.
Publicado: (2021)

Neutrophils with protumor potential could efficiently suppress tumor growth after cytokine priming and in presence of normal NK cells
por: Sun, Rui, et al.
Publicado: (2014)

Inhibition of the Histone Methyltransferase EZH2 Enhances Protumor Monocyte Recruitment in Human Mesothelioma Spheroids
por: Mola, Silvia, et al.
Publicado: (2021)

Current understanding of cancer-intrinsic PD-L1: regulation of expression and its protumoral activity
por: Yadollahi, Pedram, et al.
Publicado: (2021)

Acidic extracellular pH drives accumulation of N1-acetylspermidine and recruitment of protumor neutrophils
por: Kato, Miki, et al.
Publicado: (2023)

Protumor Effects of Histone H3–H4 Chaperone Antisilencing Feature 1B Gene on Lung Adenocarcinoma: In Silico and In Vitro Analyses
por: Wu, Liyang, et al.
Publicado: (2021)

Nanotherapy delivery of c-myc inhibitor targets Protumor Macrophages and preserves Antitumor Macrophages in Breast Cancer
por: Esser, Alison K., et al.
Publicado: (2020)

Potential therapeutic targets in the tumor microenvironment of hepatocellular carcinoma: reversing the protumor effect of tumor-associated macrophages
por: Zhou, Jingyi, et al.
Publicado: (2021)

Targeting protumor factor chitinase-3-like-1 secreted by Rab37 vesicles for cancer immunotherapy
por: Yang, Pei-Shan, et al.
Publicado: (2022)

P044: PIM kinases support protumoral and immunosuppressive phenotype and functions of macrophages in classical Hodgkin Lymphoma
por: Szydłowski, Maciej, et al.
Publicado: (2022)

Single-cell RNA sequencing and spatial transcriptomics reveal cancer-associated fibroblasts in glioblastoma with protumoral effects
por: Jain, Saket, et al.
Publicado: (2023)

The Significance of SPP1 in Lung Cancers and Its Impact as a Marker for Protumor Tumor-Associated Macrophages
por: Matsubara, Eri, et al.
Publicado: (2023)

Curcumin Reprograms TAMs from a Protumor Phenotype towards an Antitumor Phenotype via Inhibiting MAO-A/STAT6 Pathway
por: Jiang, Mingjing, et al.
Publicado: (2022)

Centromere protein U is a potential target for gene therapy of human bladder cancer
por: Wang, Sheng, et al.
Publicado: (2017)

In Vivo Double Targeting of C26 Colon Carcinoma Cells and Microenvironmental Protumor Processes Using Liposomal Simvastatin
por: Luput, Lavinia, et al.
Publicado: (2018)

Melanoma-specific bcl-2 promotes a protumoral M2-like phenotype by tumor-associated macrophages
por: Di Martile, Marta, et al.
Publicado: (2020)

CSF1R Inhibition Combined with GM-CSF Reprograms Macrophages and Disrupts Protumoral Interplays with AML Cells
por: Smirnova, Tatiana, et al.
Publicado: (2021)

Claudin-Low Breast Cancer Inflammatory Signatures Support Polarization of M1-Like Macrophages with Protumoral Activity
por: Suárez-Arriaga, Mayra Cecilia, et al.
Publicado: (2021)

Genomic Instability and Protumoral Inflammation Are Associated with Primary Resistance to Anti–PD-1 + Antiangiogenesis in Malignant Pleural Mesothelioma
por: Danlos, François-Xavier, et al.
Publicado: (2023)

Immune escape mechanisms and immunotherapy of urothelial bladder cancer
por: Yang, Zhao, et al.
Publicado: (2021)

Myeloid ERK5 deficiency suppresses tumor growth by blocking protumor macrophage polarization via STAT3 inhibition
por: Giurisato, Emanuele, et al.
Publicado: (2018)

Overexpression of Klotho Inhibits HELF Fibroblasts SASP-related Protumoral Effects on Non-small Cell Lung Cancer Cells
por: Chen, Bo, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_tshp05lhu7kv1nq95b28ujso7v