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Pleiotropic Enhancers are Ubiquitous Regulatory Elements in the Human Genome
Enhancers are regulatory elements of genomes that determine spatio-temporal patterns of gene expression. The human genome contains a vast number of enhancers, which largely outnumber protein-coding genes. Historically, enhancers have been regarded as highly tissue-specific. However, recent evidence...
Autores principales: | Laiker, Ian, Frankel, Nicolás |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156028/ https://www.ncbi.nlm.nih.gov/pubmed/35552697 http://dx.doi.org/10.1093/gbe/evac071 |
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