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Pleiotropic Enhancers are Ubiquitous Regulatory Elements in the Human Genome

Enhancers are regulatory elements of genomes that determine spatio-temporal patterns of gene expression. The human genome contains a vast number of enhancers, which largely outnumber protein-coding genes. Historically, enhancers have been regarded as highly tissue-specific. However, recent evidence...

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Detalles Bibliográficos
Autores principales: Laiker, Ian, Frankel, Nicolás
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156028/
https://www.ncbi.nlm.nih.gov/pubmed/35552697
http://dx.doi.org/10.1093/gbe/evac071

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