6-Month Evaluation of a Transcatheter Aortic Valve (Myval) in a Novel Ovine, Supra-Aortic Banding Model

The aim of the study was to evaluate a balloon expandable transcatheter heart valve (THV) system (Myval) at 6-month follow-up in ovine banding model. Eleven THV systems were implanted via carotid approach. There were 2 procedure-related deaths and 2 premature deaths. At 6 months all valves that comp...

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Detalles Bibliográficos
Autores principales: Buszman, Piotr P., Kachel, Mateusz, Ceballos, Carlos Fernandez, Łukasik, Karolina, Domaradzki, Wojciech, Pruski, Maciej, Tellez, Armando, Rousselle, Serge, Konopko, Marta, Glanc, Michał, Kaźmierczak, Paweł, Milewski, Krzysztof P., Buszman, Pawel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Preclinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156430/
https://www.ncbi.nlm.nih.gov/pubmed/35663633
http://dx.doi.org/10.1016/j.jacbts.2022.01.008
Descripción
Sumario:The aim of the study was to evaluate a balloon expandable transcatheter heart valve (THV) system (Myval) at 6-month follow-up in ovine banding model. Eleven THV systems were implanted via carotid approach. There were 2 procedure-related deaths and 2 premature deaths. At 6 months all valves that completed follow-up (n = 7) were functional, with no significant regurgitation, calcification, thrombi, or vegetation. Mean pressure gradient was 21.9 ± 11 mm Hg, maximum velocity = 3.3 ± 1 m/s, and ejection fraction was 53.3 ± 6%. Myval THV showed optimal hemodynamic performance and biocompatibility.

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