6-Month Evaluation of a Transcatheter Aortic Valve (Myval) in a Novel Ovine, Supra-Aortic Banding Model

The aim of the study was to evaluate a balloon expandable transcatheter heart valve (THV) system (Myval) at 6-month follow-up in ovine banding model. Eleven THV systems were implanted via carotid approach. There were 2 procedure-related deaths and 2 premature deaths. At 6 months all valves that comp...

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Autores principales: Buszman, Piotr P., Kachel, Mateusz, Ceballos, Carlos Fernandez, Łukasik, Karolina, Domaradzki, Wojciech, Pruski, Maciej, Tellez, Armando, Rousselle, Serge, Konopko, Marta, Glanc, Michał, Kaźmierczak, Paweł, Milewski, Krzysztof P., Buszman, Pawel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Preclinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156430/
https://www.ncbi.nlm.nih.gov/pubmed/35663633
http://dx.doi.org/10.1016/j.jacbts.2022.01.008
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author Buszman, Piotr P.
Kachel, Mateusz
Ceballos, Carlos Fernandez
Łukasik, Karolina
Domaradzki, Wojciech
Pruski, Maciej
Tellez, Armando
Rousselle, Serge
Konopko, Marta
Glanc, Michał
Kaźmierczak, Paweł
Milewski, Krzysztof P.
Buszman, Pawel E.
author_facet Buszman, Piotr P.
Kachel, Mateusz
Ceballos, Carlos Fernandez
Łukasik, Karolina
Domaradzki, Wojciech
Pruski, Maciej
Tellez, Armando
Rousselle, Serge
Konopko, Marta
Glanc, Michał
Kaźmierczak, Paweł
Milewski, Krzysztof P.
Buszman, Pawel E.
author_sort Buszman, Piotr P.
collection PubMed
description The aim of the study was to evaluate a balloon expandable transcatheter heart valve (THV) system (Myval) at 6-month follow-up in ovine banding model. Eleven THV systems were implanted via carotid approach. There were 2 procedure-related deaths and 2 premature deaths. At 6 months all valves that completed follow-up (n = 7) were functional, with no significant regurgitation, calcification, thrombi, or vegetation. Mean pressure gradient was 21.9 ± 11 mm Hg, maximum velocity = 3.3 ± 1 m/s, and ejection fraction was 53.3 ± 6%. Myval THV showed optimal hemodynamic performance and biocompatibility.
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spelling pubmed-91564302022-06-02 6-Month Evaluation of a Transcatheter Aortic Valve (Myval) in a Novel Ovine, Supra-Aortic Banding Model Buszman, Piotr P. Kachel, Mateusz Ceballos, Carlos Fernandez Łukasik, Karolina Domaradzki, Wojciech Pruski, Maciej Tellez, Armando Rousselle, Serge Konopko, Marta Glanc, Michał Kaźmierczak, Paweł Milewski, Krzysztof P. Buszman, Pawel E. JACC Basic Transl Sci Preclinical Research The aim of the study was to evaluate a balloon expandable transcatheter heart valve (THV) system (Myval) at 6-month follow-up in ovine banding model. Eleven THV systems were implanted via carotid approach. There were 2 procedure-related deaths and 2 premature deaths. At 6 months all valves that completed follow-up (n = 7) were functional, with no significant regurgitation, calcification, thrombi, or vegetation. Mean pressure gradient was 21.9 ± 11 mm Hg, maximum velocity = 3.3 ± 1 m/s, and ejection fraction was 53.3 ± 6%. Myval THV showed optimal hemodynamic performance and biocompatibility. Elsevier 2022-05-11 /pmc/articles/PMC9156430/ /pubmed/35663633 http://dx.doi.org/10.1016/j.jacbts.2022.01.008 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Preclinical Research
Buszman, Piotr P.
Kachel, Mateusz
Ceballos, Carlos Fernandez
Łukasik, Karolina
Domaradzki, Wojciech
Pruski, Maciej
Tellez, Armando
Rousselle, Serge
Konopko, Marta
Glanc, Michał
Kaźmierczak, Paweł
Milewski, Krzysztof P.
Buszman, Pawel E.
6-Month Evaluation of a Transcatheter Aortic Valve (Myval) in a Novel Ovine, Supra-Aortic Banding Model
title 6-Month Evaluation of a Transcatheter Aortic Valve (Myval) in a Novel Ovine, Supra-Aortic Banding Model
title_full 6-Month Evaluation of a Transcatheter Aortic Valve (Myval) in a Novel Ovine, Supra-Aortic Banding Model
title_fullStr 6-Month Evaluation of a Transcatheter Aortic Valve (Myval) in a Novel Ovine, Supra-Aortic Banding Model
title_full_unstemmed 6-Month Evaluation of a Transcatheter Aortic Valve (Myval) in a Novel Ovine, Supra-Aortic Banding Model
title_short 6-Month Evaluation of a Transcatheter Aortic Valve (Myval) in a Novel Ovine, Supra-Aortic Banding Model
title_sort 6-month evaluation of a transcatheter aortic valve (myval) in a novel ovine, supra-aortic banding model
topic Preclinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156430/
https://www.ncbi.nlm.nih.gov/pubmed/35663633
http://dx.doi.org/10.1016/j.jacbts.2022.01.008
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