Homophilic Interaction Between Transmembrane-JAM-A and Soluble JAM-A Regulates Thrombo-Inflammation: Implications for Coronary Artery Disease

Genetic predisposition through F11R-single-nucleotide variation (SNV) influences circulatory soluble junctional adhesion molecule-A (sJAM-A) levels in coronary artery disease (CAD) patients. Homozygous carriers of the minor alleles (F11R-SNVs rs2774276, rs790056) show enhanced levels of thrombo-infl...

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Detalles Bibliográficos
Autores principales: Rath, Dominik, Rapp, Vera, Schwartz, Jessica, Winter, Stefan, Emschermann, Frederic, Arnold, Daniel, Rheinlaender, Johannes, Büttcher, Manuela, Strebl, Michael, Braun, Michael B., Altgelt, Konstanze, Uribe, Álvaro Petersen, Schories, Christoph, Canjuga, Denis, Schaeffeler, Elke, Borst, Oliver, Schäffer, Tilman E., Langer, Harald, Stehle, Thilo, Schwab, Matthias, Geisler, Tobias, Gawaz, Meinrad, Chatterjee, Madhumita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Leading Edge Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156439/
https://www.ncbi.nlm.nih.gov/pubmed/35663628
http://dx.doi.org/10.1016/j.jacbts.2022.03.003

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