Emerging roles of Galectin-3 in diabetes and diabetes complications: A snapshot

Galectin-3 is a member of the galectin family, widely expressed in immune cells and plays a role mainly in inflammation, autoimmunity, apoptosis, and chemotaxis. We summarized the roles of Galectin-3 in diabetes and its complications, as well as the underlying mechanisms. Clinical research has deter...

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Detalles Bibliográficos
Autores principales: Li, Yanhua, Li, Tian, Zhou, Zhiguang, Xiao, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156459/
https://www.ncbi.nlm.nih.gov/pubmed/35083706
http://dx.doi.org/10.1007/s11154-021-09704-7
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author Li, Yanhua
Li, Tian
Zhou, Zhiguang
Xiao, Yang
author_facet Li, Yanhua
Li, Tian
Zhou, Zhiguang
Xiao, Yang
author_sort Li, Yanhua
collection PubMed
description Galectin-3 is a member of the galectin family, widely expressed in immune cells and plays a role mainly in inflammation, autoimmunity, apoptosis, and chemotaxis. We summarized the roles of Galectin-3 in diabetes and its complications, as well as the underlying mechanisms. Clinical research has determined that the circulating level of Galectin-3 is closely related to diabetes and its complications, thus it is promising to use Galectin-3 as a predictor and biomarker for those diseases. Galectin-3 also may be considered as an ideal therapeutic target, which has broad prospects in the prevention and treatment of diabetes and its complications, especially macrovascular and microvascular complications.
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spelling pubmed-91564592022-06-02 Emerging roles of Galectin-3 in diabetes and diabetes complications: A snapshot Li, Yanhua Li, Tian Zhou, Zhiguang Xiao, Yang Rev Endocr Metab Disord Article Galectin-3 is a member of the galectin family, widely expressed in immune cells and plays a role mainly in inflammation, autoimmunity, apoptosis, and chemotaxis. We summarized the roles of Galectin-3 in diabetes and its complications, as well as the underlying mechanisms. Clinical research has determined that the circulating level of Galectin-3 is closely related to diabetes and its complications, thus it is promising to use Galectin-3 as a predictor and biomarker for those diseases. Galectin-3 also may be considered as an ideal therapeutic target, which has broad prospects in the prevention and treatment of diabetes and its complications, especially macrovascular and microvascular complications. Springer US 2022-01-27 2022 /pmc/articles/PMC9156459/ /pubmed/35083706 http://dx.doi.org/10.1007/s11154-021-09704-7 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Li, Yanhua
Li, Tian
Zhou, Zhiguang
Xiao, Yang
Emerging roles of Galectin-3 in diabetes and diabetes complications: A snapshot
title Emerging roles of Galectin-3 in diabetes and diabetes complications: A snapshot
title_full Emerging roles of Galectin-3 in diabetes and diabetes complications: A snapshot
title_fullStr Emerging roles of Galectin-3 in diabetes and diabetes complications: A snapshot
title_full_unstemmed Emerging roles of Galectin-3 in diabetes and diabetes complications: A snapshot
title_short Emerging roles of Galectin-3 in diabetes and diabetes complications: A snapshot
title_sort emerging roles of galectin-3 in diabetes and diabetes complications: a snapshot
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156459/
https://www.ncbi.nlm.nih.gov/pubmed/35083706
http://dx.doi.org/10.1007/s11154-021-09704-7
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AT xiaoyang emergingrolesofgalectin3indiabetesanddiabetescomplicationsasnapshot

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