Blocking connexin 43 and its promotion of ATP release from renal tubular epithelial cells ameliorates renal fibrosis

Whether metabolites derived from injured renal tubular epithelial cells (TECs) participate in renal fibrosis is poorly explored. After TEC injury, various metabolites are released and among the most potent is adenosine triphosphate (ATP), which is released via ATP-permeable channels. In these hemich...

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Detalles Bibliográficos
Autores principales: Xu, Huzi, Wang, Meng, Li, Yinzheng, Shi, Mengxia, Wang, Zheng, Cao, Chujin, Hong, Yu, Hu, Bin, Zhu, Han, Zhao, Zhi, Chu, Xiaoxin, Zhu, Fan, Deng, Xuan, Wu, Jianliang, Zhao, Fenfei, Guo, Jing, Wang, Yuxi, Pei, Guangchang, Zhu, Fengming, Wang, Xiaoyan, Yang, Juan, Yao, Ying, Zeng, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156700/
https://www.ncbi.nlm.nih.gov/pubmed/35641484
http://dx.doi.org/10.1038/s41419-022-04910-w

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