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PFKP alleviates glucose starvation-induced metabolic stress in lung cancer cells via AMPK-ACC2 dependent fatty acid oxidation
Cancer cells adopt metabolic reprogramming to promote cell survival under metabolic stress. A key regulator of cell metabolism is AMP-activated protein kinase (AMPK) which promotes catabolism while suppresses anabolism. However, the underlying mechanism of AMPK in handling metabolic stress in cancer...
Autores principales: | Chen, Jiaqing, Zou, Li, Lu, Guang, Grinchuk, Oleg, Fang, Lei, Ong, Derrick Sek Tong, Taneja, Reshma, Ong, Choon-Nam, Shen, Han-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156709/ https://www.ncbi.nlm.nih.gov/pubmed/35641476 http://dx.doi.org/10.1038/s41421-022-00406-1 |
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