PFKP alleviates glucose starvation-induced metabolic stress in lung cancer cells via AMPK-ACC2 dependent fatty acid oxidation

Cancer cells adopt metabolic reprogramming to promote cell survival under metabolic stress. A key regulator of cell metabolism is AMP-activated protein kinase (AMPK) which promotes catabolism while suppresses anabolism. However, the underlying mechanism of AMPK in handling metabolic stress in cancer...

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Detalles Bibliográficos
Autores principales: Chen, Jiaqing, Zou, Li, Lu, Guang, Grinchuk, Oleg, Fang, Lei, Ong, Derrick Sek Tong, Taneja, Reshma, Ong, Choon-Nam, Shen, Han-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156709/
https://www.ncbi.nlm.nih.gov/pubmed/35641476
http://dx.doi.org/10.1038/s41421-022-00406-1

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