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Functional and phylogenetic analysis of TetX variants to design a new classification system

Recently, many TetX variants such as Tet(X3~14) were reported to confer resistance to tigecycline which is a last-resort antibiotic used to treat infections caused by multidrug-resistant bacteria. In this study, we identified essential residues including 329, 339, 340, 350, and 351 in TetX variants...

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Detalles Bibliográficos
Autores principales:	Cheng, Qipeng, Cheung, Yanchu, Liu, Chenyu, Chan, Edward Wai Chi, Wong, Kwok Yin, Zhang, Rong, Chen, Sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156754/ https://www.ncbi.nlm.nih.gov/pubmed/35641548 http://dx.doi.org/10.1038/s42003-022-03465-y

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