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Cannabinoid Receptor-1 suppresses M2 macrophage polarization in colorectal cancer by downregulating EGFR

Cannabinoid receptors, CB1 and CB2, have been implicated as emerging targets for cancer therapy. Herein, we investigated the potential regulation mechanism of CB1 and its implications in colorectal cancer. CB1 and EGFR expression were examined in colorectal cancer cell lines. The effects of CB1 agon...

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Detalles Bibliográficos
Autores principales:	Deng, You-Ming, Zhao, Cheng, Wu, Lei, Qu, Zhan, Wang, Xin-Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156763/ https://www.ncbi.nlm.nih.gov/pubmed/35641479 http://dx.doi.org/10.1038/s41420-022-01064-8

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