The Ube2m-Rbx1 neddylation-Cullin-RING-Ligase proteins are essential for the maintenance of Regulatory T cell fitness

Neddylation-mediated activation of Cullin-RING E3 Ligases (CRLs) are necessary for the degradation of specific immune regulatory proteins. However, little is known about how these processes govern the function of regulatory T (Treg) cells. Here we show that mice with Treg cell-specific deletion of R...

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Detalles Bibliográficos
Autores principales: Wu, Di, Li, Haomin, Liu, Mingwei, Qin, Jun, Sun, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156764/
https://www.ncbi.nlm.nih.gov/pubmed/35641500
http://dx.doi.org/10.1038/s41467-022-30707-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156764/
https://www.ncbi.nlm.nih.gov/pubmed/35641500
http://dx.doi.org/10.1038/s41467-022-30707-8

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