Computationally designed hyperactive Cas9 enzymes

The ability to alter the genomes of living cells is key to understanding how genes influence the functions of organisms and will be critical to modify living systems for useful purposes. However, this promise has long been limited by the technical challenges involved in genetic engineering. Recent a...

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Detalles Bibliográficos
Autores principales: Vos, Pascal D., Rossetti, Giulia, Mantegna, Jessica L., Siira, Stefan J., Gandadireja, Andrianto P., Bruce, Mitchell, Raven, Samuel A., Khersonsky, Olga, Fleishman, Sarel J., Filipovska, Aleksandra, Rackham, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156780/
https://www.ncbi.nlm.nih.gov/pubmed/35641498
http://dx.doi.org/10.1038/s41467-022-30598-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156780/
https://www.ncbi.nlm.nih.gov/pubmed/35641498
http://dx.doi.org/10.1038/s41467-022-30598-9

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