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Computationally designed hyperactive Cas9 enzymes
The ability to alter the genomes of living cells is key to understanding how genes influence the functions of organisms and will be critical to modify living systems for useful purposes. However, this promise has long been limited by the technical challenges involved in genetic engineering. Recent a...
Autores principales: | Vos, Pascal D., Rossetti, Giulia, Mantegna, Jessica L., Siira, Stefan J., Gandadireja, Andrianto P., Bruce, Mitchell, Raven, Samuel A., Khersonsky, Olga, Fleishman, Sarel J., Filipovska, Aleksandra, Rackham, Oliver |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156780/ https://www.ncbi.nlm.nih.gov/pubmed/35641498 http://dx.doi.org/10.1038/s41467-022-30598-9 |
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