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Novel sustainable filter for virus filtration and inactivation

The COVID-19 pandemic has caused a multi-scale impact on the world population that started from a nano-scale respiratory virus and led to the shutdown of macro-scale economies. Direct transmission of SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) and its variants through aerosolized dr...

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Autores principales: Purwar, Tanya, Esquivel-Puentes, Helber Antonio, Pulletikurthi, Venkatesh, Li, Xing, Doosttalab, Ali, Nelson, Clarice E., Appiah, Rita E., Blatchley, Ernest R., Castano, Victor, Castillo, Luciano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156824/
https://www.ncbi.nlm.nih.gov/pubmed/35650235
http://dx.doi.org/10.1038/s41598-022-13316-9
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author Purwar, Tanya
Esquivel-Puentes, Helber Antonio
Pulletikurthi, Venkatesh
Li, Xing
Doosttalab, Ali
Nelson, Clarice E.
Appiah, Rita E.
Blatchley, Ernest R.
Castano, Victor
Castillo, Luciano
author_facet Purwar, Tanya
Esquivel-Puentes, Helber Antonio
Pulletikurthi, Venkatesh
Li, Xing
Doosttalab, Ali
Nelson, Clarice E.
Appiah, Rita E.
Blatchley, Ernest R.
Castano, Victor
Castillo, Luciano
author_sort Purwar, Tanya
collection PubMed
description The COVID-19 pandemic has caused a multi-scale impact on the world population that started from a nano-scale respiratory virus and led to the shutdown of macro-scale economies. Direct transmission of SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) and its variants through aerosolized droplets is a major contributor towards increasing cases of this infection. To curb the spread, one of the best engineered solutions is the use of face masks to prevent the passage of infectious saliva micro-droplets from an infected person to a healthy person. The commercially available masks are single use, passive face-piece filters. These become difficult to breathe in during strenuous activities. Also, they need to be disposed regularly due to accumulation of unwanted particulate and pathogens over time. Frequent disposal of these masks is unsustainable for the environment. In this study, we have proposed a novel design for a filter for enhanced virus filtration, better breathability, and virus inactivation over time. The filter is called Hy–Cu named after its (Hy) drophobic properties and another significant layer comprises of copper (Cu). The breathability (pressure drop across filter) of Hy–Cu is tested and compared with widely used surgical masks and KN95 masks, both experimentally and numerically. The results show that the Hy–Cu filter offers at least 10% less air resistance as compared to commercially available masks. The experimental results on virus filtration and inactivation tests using MS2 bacteriophage (a similar protein structure as SARS-CoV-2) show that the novel filter has 90% filtering efficiency and 99% virus inactivation over a period of 2 h. This makes the Hy–Cu filter reusable and a judicious substitute to the single use masks.
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spelling pubmed-91568242022-06-02 Novel sustainable filter for virus filtration and inactivation Purwar, Tanya Esquivel-Puentes, Helber Antonio Pulletikurthi, Venkatesh Li, Xing Doosttalab, Ali Nelson, Clarice E. Appiah, Rita E. Blatchley, Ernest R. Castano, Victor Castillo, Luciano Sci Rep Article The COVID-19 pandemic has caused a multi-scale impact on the world population that started from a nano-scale respiratory virus and led to the shutdown of macro-scale economies. Direct transmission of SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) and its variants through aerosolized droplets is a major contributor towards increasing cases of this infection. To curb the spread, one of the best engineered solutions is the use of face masks to prevent the passage of infectious saliva micro-droplets from an infected person to a healthy person. The commercially available masks are single use, passive face-piece filters. These become difficult to breathe in during strenuous activities. Also, they need to be disposed regularly due to accumulation of unwanted particulate and pathogens over time. Frequent disposal of these masks is unsustainable for the environment. In this study, we have proposed a novel design for a filter for enhanced virus filtration, better breathability, and virus inactivation over time. The filter is called Hy–Cu named after its (Hy) drophobic properties and another significant layer comprises of copper (Cu). The breathability (pressure drop across filter) of Hy–Cu is tested and compared with widely used surgical masks and KN95 masks, both experimentally and numerically. The results show that the Hy–Cu filter offers at least 10% less air resistance as compared to commercially available masks. The experimental results on virus filtration and inactivation tests using MS2 bacteriophage (a similar protein structure as SARS-CoV-2) show that the novel filter has 90% filtering efficiency and 99% virus inactivation over a period of 2 h. This makes the Hy–Cu filter reusable and a judicious substitute to the single use masks. Nature Publishing Group UK 2022-06-01 /pmc/articles/PMC9156824/ /pubmed/35650235 http://dx.doi.org/10.1038/s41598-022-13316-9 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Purwar, Tanya
Esquivel-Puentes, Helber Antonio
Pulletikurthi, Venkatesh
Li, Xing
Doosttalab, Ali
Nelson, Clarice E.
Appiah, Rita E.
Blatchley, Ernest R.
Castano, Victor
Castillo, Luciano
Novel sustainable filter for virus filtration and inactivation
title Novel sustainable filter for virus filtration and inactivation
title_full Novel sustainable filter for virus filtration and inactivation
title_fullStr Novel sustainable filter for virus filtration and inactivation
title_full_unstemmed Novel sustainable filter for virus filtration and inactivation
title_short Novel sustainable filter for virus filtration and inactivation
title_sort novel sustainable filter for virus filtration and inactivation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156824/
https://www.ncbi.nlm.nih.gov/pubmed/35650235
http://dx.doi.org/10.1038/s41598-022-13316-9
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