Global-run on sequencing identifies Gm11967 as an Akt-dependent long noncoding RNA involved in insulin sensitivity

The insulin responsive Akt and FoxO1 signaling axis is a key regulator of the hepatic transcriptional response to nutrient intake. Here, we used global run-on sequencing (GRO-seq) to measure the nascent transcriptional response to fasting and refeeding as well as define the specific role of hepatic...

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Detalles Bibliográficos
Autores principales: Santoleri, Dominic, Lim, Hee-Woong, Emmett, Matthew J., Stoute, Julian, Gavin, Matthew J., Sostre-Colón, Jaimarie, Uehara, Kahealani, Welles, Jaclyn E., Liu, Kathy Fange, Lazar, Mitchell A., Titchenell, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156944/
https://www.ncbi.nlm.nih.gov/pubmed/35663017
http://dx.doi.org/10.1016/j.isci.2022.104410

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