Loss of mitochondrial ATPase ATAD3A contributes to nonalcoholic fatty liver disease through accumulation of lipids and damaged mitochondria

Mitochondrial ATPase ATAD3A is essential for cholesterol transport, mitochondrial structure, and cell survival. However, the relationship between ATAD3A and nonalcoholic fatty liver disease (NAFLD) is largely unknown. In this study, we found that ATAD3A was upregulated in the progression of NAFLD in...

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Detalles Bibliográficos
Autores principales: Chen, Liting, Li, Yuchang, Sottas, Chantal, Lazaris, Anthoula, Petrillo, Stephanie K., Metrakos, Peter, Li, Lu, Ishida, Yuji, Saito, Takeshi, Garza, Samuel, Papadopoulos, Vassilios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157002/
https://www.ncbi.nlm.nih.gov/pubmed/35513069
http://dx.doi.org/10.1016/j.jbc.2022.102008

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