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Genetic analysis of daf-18/PTEN missense mutants for starvation resistance and developmental regulation during Caenorhabditis elegans L1 arrest

Mutations in the well-known tumor suppressor PTEN are observed in many cancers. PTEN is a dual-specificity phosphatase that harbors lipid and protein-phosphatase activities. The Caenorhabditis elegans PTEN ortholog is daf-18, which has pleiotropic effects on dauer formation, aging, starvation resist...

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Detalles Bibliográficos
Autores principales:	Chen, Jingxian, Tang, Linda Y, Powell, Maya E, Jordan, James M, Baugh, L Ryan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157142/ https://www.ncbi.nlm.nih.gov/pubmed/35451480 http://dx.doi.org/10.1093/g3journal/jkac092

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