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RBBP4 dysfunction reshapes the genomic landscape of H3K27 methylation and acetylation and disrupts gene expression

RBBP4 is a subunit of the chromatin remodeling complexes known as Polycomb repressive complex 2 and histone deacetylase 1/2-containing complexes. These complexes are responsible for histone H3 lysine 27 methylation and deacetylation, respectively. How RBBP4 modulates the functions of these complexes...

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Detalles Bibliográficos
Autores principales: Mu, Weipeng, Murcia, Noel S, Smith, Keriayn N, Menon, Debashish U, Yee, Della, Magnuson, Terry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157164/
https://www.ncbi.nlm.nih.gov/pubmed/35416979
http://dx.doi.org/10.1093/g3journal/jkac082