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Alpha lipoic acid reverses scopolamine-induced spatial memory loss and pyramidal cell neurodegeneration in the prefrontal cortex of Wistar rats

Neurodegenerative disorders are linked to oxidative tissue damage characterized by gradual loss of cognitive functions and neuronal cells. Alpha-lipoic acid (AHA) has a strong antioxidant property. Scopolamine is an anti-muscarinic agent used to study the mechanism of memory loss in an animal model....

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Detalles Bibliográficos
Autores principales: Memudu, Adejoke Elizabeth, Adanike, Rukky Precious
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157193/
https://www.ncbi.nlm.nih.gov/pubmed/35664083
http://dx.doi.org/10.1016/j.ibneur.2022.05.005