Extracellular vesicles carry distinct proteo-transcriptomic signatures that are different from their cancer cell of origin

Circulating extracellular vesicles (EVs) contain molecular footprints—lipids, proteins, RNA, and DNA—from their cell of origin. Consequently, EV-associated RNA and proteins have gained widespread interest as liquid-biopsy biomarkers. Yet, an integrative proteo-transcriptomic landscape of EVs and com...

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Detalles Bibliográficos
Autores principales: Chen, Tzu-Yi, Gonzalez-Kozlova, Edgar, Soleymani, Taliah, La Salvia, Sabrina, Kyprianou, Natasha, Sahoo, Susmita, Tewari, Ashutosh K., Cordon-Cardo, Carlos, Stolovitzky, Gustavo, Dogra, Navneet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157216/
https://www.ncbi.nlm.nih.gov/pubmed/35663013
http://dx.doi.org/10.1016/j.isci.2022.104414

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