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Aloe-Emodin Induces Mitochondrial Dysfunction and Pyroptosis by Activation of the Caspase-9/3/Gasdermin E Axis in HeLa Cells

Aloe-emodin (1,8-dihydroxy-3-hydroxymethyl-anthraquinone), derived from some Chinese edible medicinal herbs, exerts a potential anticancer activity on various cancer cells, making it a drug candidate for cancer therapy. Yet, the role of aloe-emodin in pyroptosis, a new type of cell death, is unchara...

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Detalles Bibliográficos
Autores principales:	Li, Tonghui, Shi, Liuliu, Liu, Wenqiang, Hu, Xuhao, Hui, Yuanjian, Di, Maojun, Xue, Shen, Zheng, Yan, Yao, Mengjuan, Li, Chen, Meng, Kun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157280/ https://www.ncbi.nlm.nih.gov/pubmed/35662735 http://dx.doi.org/10.3389/fphar.2022.854526

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