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The association between body dysmorphic symptoms and suicidality among adolescents and young adults: a genetically informative study

BACKGROUND: Previous research indicates that body dysmorphic disorder (BDD) is associated with risk of suicidality. However, studies have relied on small and/or specialist samples and largely focussed on adults, despite these difficulties commonly emerging in youth. Furthermore, the aetiology of the...

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Autores principales: Krebs, Georgina, Fernández de la Cruz, Lorena, Rijsdijk, Frühling V., Rautio, Daniel, Enander, Jesper, Rück, Christian, Lichtenstein, Paul, Lundström, Sebastian, Larsson, Henrik, Eley, Thalia C., Mataix-Cols, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157307/
https://www.ncbi.nlm.nih.gov/pubmed/32940195
http://dx.doi.org/10.1017/S0033291720002998
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author Krebs, Georgina
Fernández de la Cruz, Lorena
Rijsdijk, Frühling V.
Rautio, Daniel
Enander, Jesper
Rück, Christian
Lichtenstein, Paul
Lundström, Sebastian
Larsson, Henrik
Eley, Thalia C.
Mataix-Cols, David
author_facet Krebs, Georgina
Fernández de la Cruz, Lorena
Rijsdijk, Frühling V.
Rautio, Daniel
Enander, Jesper
Rück, Christian
Lichtenstein, Paul
Lundström, Sebastian
Larsson, Henrik
Eley, Thalia C.
Mataix-Cols, David
author_sort Krebs, Georgina
collection PubMed
description BACKGROUND: Previous research indicates that body dysmorphic disorder (BDD) is associated with risk of suicidality. However, studies have relied on small and/or specialist samples and largely focussed on adults, despite these difficulties commonly emerging in youth. Furthermore, the aetiology of the relationship remains unknown. METHODS: Two independent twin samples were identified through the Child and Adolescent Twin Study in Sweden, at ages 18 (N = 6027) and 24 (N = 3454). Participants completed a self-report measure of BDD symptom severity. Young people and parents completed items assessing suicidal ideation/behaviours. Logistic regression models tested the association of suicidality outcomes with: (a) probable BDD, classified using an empirically derived cut-off; and (b) continuous scores of BDD symptoms. Bivariate genetic models examined the aetiology of the association between BDD symptoms and suicidality at both ages. RESULTS: Suicidal ideation and behaviours were common among those with probable BDD at both ages. BDD symptoms, measured continuously, were linked with all aspects of suicidality, and associations generally remained significant after adjusting for depressive and anxiety symptoms. Genetic factors accounted for most of the covariance between BDD symptoms and suicidality (72.9 and 77.7% at ages 18 and 24, respectively), but with significant non-shared environmental influences (27.1 and 22.3% at ages 18 and 24, respectively). CONCLUSIONS: BDD symptoms are associated with a substantial risk of suicidal ideation and behaviours in late adolescence and early adulthood. This relationship is largely explained by common genetic liability, but non-shared environmental effects are also significant and could provide opportunities for prevention among those at high-risk.
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spelling pubmed-91573072022-06-16 The association between body dysmorphic symptoms and suicidality among adolescents and young adults: a genetically informative study Krebs, Georgina Fernández de la Cruz, Lorena Rijsdijk, Frühling V. Rautio, Daniel Enander, Jesper Rück, Christian Lichtenstein, Paul Lundström, Sebastian Larsson, Henrik Eley, Thalia C. Mataix-Cols, David Psychol Med Original Article BACKGROUND: Previous research indicates that body dysmorphic disorder (BDD) is associated with risk of suicidality. However, studies have relied on small and/or specialist samples and largely focussed on adults, despite these difficulties commonly emerging in youth. Furthermore, the aetiology of the relationship remains unknown. METHODS: Two independent twin samples were identified through the Child and Adolescent Twin Study in Sweden, at ages 18 (N = 6027) and 24 (N = 3454). Participants completed a self-report measure of BDD symptom severity. Young people and parents completed items assessing suicidal ideation/behaviours. Logistic regression models tested the association of suicidality outcomes with: (a) probable BDD, classified using an empirically derived cut-off; and (b) continuous scores of BDD symptoms. Bivariate genetic models examined the aetiology of the association between BDD symptoms and suicidality at both ages. RESULTS: Suicidal ideation and behaviours were common among those with probable BDD at both ages. BDD symptoms, measured continuously, were linked with all aspects of suicidality, and associations generally remained significant after adjusting for depressive and anxiety symptoms. Genetic factors accounted for most of the covariance between BDD symptoms and suicidality (72.9 and 77.7% at ages 18 and 24, respectively), but with significant non-shared environmental influences (27.1 and 22.3% at ages 18 and 24, respectively). CONCLUSIONS: BDD symptoms are associated with a substantial risk of suicidal ideation and behaviours in late adolescence and early adulthood. This relationship is largely explained by common genetic liability, but non-shared environmental effects are also significant and could provide opportunities for prevention among those at high-risk. Cambridge University Press 2022-05 2020-09-17 /pmc/articles/PMC9157307/ /pubmed/32940195 http://dx.doi.org/10.1017/S0033291720002998 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Krebs, Georgina
Fernández de la Cruz, Lorena
Rijsdijk, Frühling V.
Rautio, Daniel
Enander, Jesper
Rück, Christian
Lichtenstein, Paul
Lundström, Sebastian
Larsson, Henrik
Eley, Thalia C.
Mataix-Cols, David
The association between body dysmorphic symptoms and suicidality among adolescents and young adults: a genetically informative study
title The association between body dysmorphic symptoms and suicidality among adolescents and young adults: a genetically informative study
title_full The association between body dysmorphic symptoms and suicidality among adolescents and young adults: a genetically informative study
title_fullStr The association between body dysmorphic symptoms and suicidality among adolescents and young adults: a genetically informative study
title_full_unstemmed The association between body dysmorphic symptoms and suicidality among adolescents and young adults: a genetically informative study
title_short The association between body dysmorphic symptoms and suicidality among adolescents and young adults: a genetically informative study
title_sort association between body dysmorphic symptoms and suicidality among adolescents and young adults: a genetically informative study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157307/
https://www.ncbi.nlm.nih.gov/pubmed/32940195
http://dx.doi.org/10.1017/S0033291720002998
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