Fueling the fire in the gut

Gut dysbiosis has long been associated with the development of Crohn’s disease and other gastrointestinal disorders. Otake-Kasamoto et al. (2022. J. Exp. Med. https://doi.org/10.1084/jem.20211291) report that dysbiotic microbiota-derived bioactive lipids, lysophosphatidylserines, can promote patholo...

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Detalles Bibliográficos
Autores principales: Lin, Chia-Hao, Lu, Li-Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Insights
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157397/
https://www.ncbi.nlm.nih.gov/pubmed/35621881
http://dx.doi.org/10.1084/jem.20220723
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author Lin, Chia-Hao
Lu, Li-Fan
author_facet Lin, Chia-Hao
Lu, Li-Fan
author_sort Lin, Chia-Hao
collection PubMed
description Gut dysbiosis has long been associated with the development of Crohn’s disease and other gastrointestinal disorders. Otake-Kasamoto et al. (2022. J. Exp. Med. https://doi.org/10.1084/jem.20211291) report that dysbiotic microbiota-derived bioactive lipids, lysophosphatidylserines, can promote pathological Th1 cell responses through inducing metabolic reprogramming and epigenetic changes.
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spelling pubmed-91573972023-01-04 Fueling the fire in the gut Lin, Chia-Hao Lu, Li-Fan J Exp Med Insights Gut dysbiosis has long been associated with the development of Crohn’s disease and other gastrointestinal disorders. Otake-Kasamoto et al. (2022. J. Exp. Med. https://doi.org/10.1084/jem.20211291) report that dysbiotic microbiota-derived bioactive lipids, lysophosphatidylserines, can promote pathological Th1 cell responses through inducing metabolic reprogramming and epigenetic changes. Rockefeller University Press 2022-05-27 /pmc/articles/PMC9157397/ /pubmed/35621881 http://dx.doi.org/10.1084/jem.20220723 Text en © 2022 Lin and Lu https://creativecommons.org/licenses/by-nc-sa/4.0/http://www.rupress.org/terms/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Insights
Lin, Chia-Hao
Lu, Li-Fan
Fueling the fire in the gut
title Fueling the fire in the gut
title_full Fueling the fire in the gut
title_fullStr Fueling the fire in the gut
title_full_unstemmed Fueling the fire in the gut
title_short Fueling the fire in the gut
title_sort fueling the fire in the gut
topic Insights
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157397/
https://www.ncbi.nlm.nih.gov/pubmed/35621881
http://dx.doi.org/10.1084/jem.20220723
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