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Triosephosphate isomerase of Streptococcus pneumoniae is released extracellularly by autolysis and binds to host plasminogen to promote its activation

Recruitment of plasminogen is an important infection strategy of the human pathogen Streptococcus pneumoniae to invade host tissues. In Streptococcus aureus, triosephosphate isomerase (TPI) has been reported to bind plasminogen. In this study, the TPI of S. pneumoniae (TpiA) was identified through p...

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Detalles Bibliográficos
Autores principales: Hirayama, Satoru, Domon, Hisanori, Hiyoshi, Takumi, Isono, Toshihito, Tamura, Hikaru, Sasagawa, Karin, Takizawa, Fumio, Terao, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157410/
https://www.ncbi.nlm.nih.gov/pubmed/35298875
http://dx.doi.org/10.1002/2211-5463.13396