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Disseminated paracoccidioidomycosis associated with lymph node tuberculosis in a non immunocompromised child
The association of paracoccidioidomycosis (PCM) and tuberculosis (TB) produces an uncommon hyperinflammatory syndrome, causing multiorgan dysfunction. TB associated PCM is a rare condition, but it is fatal if not treated. Herein, we present a immunocompetent child who is admitted for fever and painf...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157441/ https://www.ncbi.nlm.nih.gov/pubmed/35663608 http://dx.doi.org/10.1016/j.idcr.2022.e01507 |
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author | Montalvo, Raúl Díaz, Anibal Montalvo, Josdan Pomazongo, Manuel Montalvo, Miguel Tunque, Edison |
author_facet | Montalvo, Raúl Díaz, Anibal Montalvo, Josdan Pomazongo, Manuel Montalvo, Miguel Tunque, Edison |
author_sort | Montalvo, Raúl |
collection | PubMed |
description | The association of paracoccidioidomycosis (PCM) and tuberculosis (TB) produces an uncommon hyperinflammatory syndrome, causing multiorgan dysfunction. TB associated PCM is a rare condition, but it is fatal if not treated. Herein, we present a immunocompetent child who is admitted for fever and painful lymphadenopathy, with evidence of acid-alcohol-resistant bacillus (AARB) in cervical lymph node biopsy, antituberculous treatment was started with partial clinical improvement and is given discharge from hospital. At 3 weeks, he was readmitted by fever, weight loss, dyspnea and a greater number of adenopathies, in the new biopsy multiple yeasts were found compatible with PCM, our patient responded well to the combination of antituberculosis therapy(ATT), corticosteroid, and amphotericin B deoxycholate, presenting clinical improvement and subsequently continued with itraconazole. |
format | Online Article Text |
id | pubmed-9157441 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-91574412022-06-02 Disseminated paracoccidioidomycosis associated with lymph node tuberculosis in a non immunocompromised child Montalvo, Raúl Díaz, Anibal Montalvo, Josdan Pomazongo, Manuel Montalvo, Miguel Tunque, Edison IDCases Case Report The association of paracoccidioidomycosis (PCM) and tuberculosis (TB) produces an uncommon hyperinflammatory syndrome, causing multiorgan dysfunction. TB associated PCM is a rare condition, but it is fatal if not treated. Herein, we present a immunocompetent child who is admitted for fever and painful lymphadenopathy, with evidence of acid-alcohol-resistant bacillus (AARB) in cervical lymph node biopsy, antituberculous treatment was started with partial clinical improvement and is given discharge from hospital. At 3 weeks, he was readmitted by fever, weight loss, dyspnea and a greater number of adenopathies, in the new biopsy multiple yeasts were found compatible with PCM, our patient responded well to the combination of antituberculosis therapy(ATT), corticosteroid, and amphotericin B deoxycholate, presenting clinical improvement and subsequently continued with itraconazole. Elsevier 2022-05-20 /pmc/articles/PMC9157441/ /pubmed/35663608 http://dx.doi.org/10.1016/j.idcr.2022.e01507 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Montalvo, Raúl Díaz, Anibal Montalvo, Josdan Pomazongo, Manuel Montalvo, Miguel Tunque, Edison Disseminated paracoccidioidomycosis associated with lymph node tuberculosis in a non immunocompromised child |
title | Disseminated paracoccidioidomycosis associated with lymph node tuberculosis in a non immunocompromised child |
title_full | Disseminated paracoccidioidomycosis associated with lymph node tuberculosis in a non immunocompromised child |
title_fullStr | Disseminated paracoccidioidomycosis associated with lymph node tuberculosis in a non immunocompromised child |
title_full_unstemmed | Disseminated paracoccidioidomycosis associated with lymph node tuberculosis in a non immunocompromised child |
title_short | Disseminated paracoccidioidomycosis associated with lymph node tuberculosis in a non immunocompromised child |
title_sort | disseminated paracoccidioidomycosis associated with lymph node tuberculosis in a non immunocompromised child |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157441/ https://www.ncbi.nlm.nih.gov/pubmed/35663608 http://dx.doi.org/10.1016/j.idcr.2022.e01507 |
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