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Associations of DNA methylation algorithms of aging and cancer risk: Results from a prospective cohort study

BACKGROUND: Previous studies have shown that three DNA methylation (DNAm) based algorithms of aging, DNAm PhenoAge acceleration (AgeAccelPheno), DNAm GrimAge acceleration (AgeAccelGrim), and mortality risk score (MRscore), to be strong predictors of mortality and aging related outcomes. We aimed to...

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Detalles Bibliográficos
Autores principales: Li, Xiangwei, Schöttker, Ben, Holleczek, Bernd, Brenner, Hermann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157462/
https://www.ncbi.nlm.nih.gov/pubmed/35636319
http://dx.doi.org/10.1016/j.ebiom.2022.104083