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Inhibition of glutathione metabolism can limit the development of pancreatic cancer

Pharmacological inhibitors of glutathione synthesis and circulation, such as buthionine-sulfoximine, inhibit glutathione metabolism. These drugs decrease the aggressiveness of pancreatic cancer, inhibit tumor stem cell survival, and reduce chemotherapy resistance. Nevertheless, buthionine-sulfoximin...

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Detalles Bibliográficos
Autores principales: Cai, Pei-Yuan, Ma, Mei-Lin, Zhang, Yang-Fen, Zhou, Zi-Xuan, Wang, Yan, He, Lian-Ping, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157600/
https://www.ncbi.nlm.nih.gov/pubmed/35722199
http://dx.doi.org/10.4252/wjsc.v14.i5.362