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Identification of Synergistic Drug Combinations to Target KRAS-Driven Chemoradioresistant Cancers Utilizing Tumoroid Models of Colorectal Adenocarcinoma and Recurrent Glioblastoma

Treatment resistance is observed in all advanced cancers. Colorectal cancer (CRC) presenting as colorectal adenocarcinoma (COAD) is the second leading cause of cancer deaths worldwide. Multimodality treatment includes surgery, chemotherapy, and targeted therapies with selective utilization of immuno...

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Detalles Bibliográficos
Autores principales:	Gupta, Kshama, Jones, Jeremy C., Farias, Virginea De Araujo, Mackeyev, Yuri, Singh, Pankaj K., Quiñones-Hinojosa, Alfredo, Krishnan, Sunil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9158132/ https://www.ncbi.nlm.nih.gov/pubmed/35664781 http://dx.doi.org/10.3389/fonc.2022.840241

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