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Zibotentan in systemic sclerosis-associated chronic kidney disease: a phase II randomised placebo-controlled trial
BACKGROUND: We report results from a phase II randomised placebo-controlled trial assessing zibotentan, a highly selective endothelin receptor antagonist (ERA), in chronic kidney disease (CKD) secondary to systemic sclerosis (SSc). METHODS: This trial included three sub-studies: ZEBRA 1—a randomised...
Autores principales: | Stern, Edward P., Host, Lauren V., Wanjiku, Ivy, Escott, K. Jane, Gilmour, Peter S., Ochiel, Rachel, Unwin, Robert, Burns, Aine, Ong, Voon H., Cadiou, Helen, O’Keeffe, Aidan G., Denton, Christopher P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9158153/ https://www.ncbi.nlm.nih.gov/pubmed/35650639 http://dx.doi.org/10.1186/s13075-022-02818-6 |
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