Mapping the genetic landscape of early-onset Alzheimer’s disease in a cohort of 36 families

BACKGROUND: Many families with clinical early-onset Alzheimer’s disease (EOAD) remain genetically unexplained. A combination of genetic factors is not standardly investigated. In addition to monogenic causes, we evaluated the possible polygenic architecture in a large series of families, to assess i...

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Detalles Bibliográficos
Autores principales: Mol, Merel O., van der Lee, Sven J., Hulsman, Marc, Pijnenburg, Yolande A. L., Scheltens, Phillip, Seelaar, Harro, van Swieten, John C., Kaat, Laura Donker, Holstege, Henne, van Rooij, Jeroen G. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9158156/
https://www.ncbi.nlm.nih.gov/pubmed/35650585
http://dx.doi.org/10.1186/s13195-022-01018-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9158156/
https://www.ncbi.nlm.nih.gov/pubmed/35650585
http://dx.doi.org/10.1186/s13195-022-01018-3

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