Cargando…

Efficacy and safety of Gyejibokryeong-hwan (GBH) in major depressive disorder: study protocol for multicentre randomised controlled trial

BACKGROUND: Gyejibokryeong-hwan (GBH) is an herbal medicine composed of five herbs. It has been widely used to treat gynaecological diseases in traditional East Asian medicine. Recent animal studies suggest antidepressant effects of GBH. In this trial, we explore the efficacy and safety of GBH in pa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Choi, Yujin, Jung, In Chul, Kim, Ju Yeon, Cho, Seung-Hun, Kim, Yunna, Chung, Sun-Yong, Kwak, Hui-Yong, Lee, Doo Suk, Lee, Wonwoo, Nam, In-Jeong, Yang, Changsop, Lee, Mi Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Study Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9158297/ https://www.ncbi.nlm.nih.gov/pubmed/35650612 http://dx.doi.org/10.1186/s13063-022-06339-0

Ejemplares similares

The genotoxicity of an aqueous extract of Gyejibokryeong-hwan
por: Lee, Mee-Young, et al.
Publicado: (2018)

Antineuroinflammatory and Neuroprotective Effects of Gyejibokryeong-Hwan in Lipopolysaccharide-Stimulated BV2 Microglia
por: Park, Bo-Kyung, et al.
Publicado: (2019)

Antidepressant-Like Effects of Gyejibokryeong-hwan in a Mouse Model of Reserpine-Induced Depression
por: Park, Bo-Kyung, et al.
Publicado: (2018)

Elucidating the potential pharmaceutical mechanism of Gyejibokryeong-hwan on rosacea using network analysis
por: Kim, Jundong, et al.
Publicado: (2023)

Exploring the Mechanism of Gyejibokryeong-hwan against Atherosclerosis Using Network Pharmacology and Molecular Docking
por: Lee, A Yeong, et al.
Publicado: (2020)

Beneficial effect of Gyejibokryeong-hwan on climacteric syndrome with blood stasis pattern: A randomized, double-blinded, placebo-controlled clinical pilot trial
por: Han, Kyungsun, et al.
Publicado: (2023)

Bangpungtongsung-san for patients with major depressive disorder: study protocol for a randomized controlled phase II clinical trial
por: Kim, Yunna, et al.
Publicado: (2023)

Gyejibongneyong-hwan, a herbal medicine for the treatment of dysmenorrhoea with uterine fibroids: a protocol for a randomised controlled trial
por: Jung, Jeeyoun, et al.
Publicado: (2016)

Herbal medicine (Gyejibongneyong-hwan) for treating primary dysmenorrhoea: a protocol for a systematic review of randomised controlled trials
por: Lee, Ju Ah, et al.
Publicado: (2016)

Effectiveness of Gyejibongnyeong-Hwan for shoulder pain: study protocol for a randomised, wait-list controlled pilot trial
por: Jang, Soobin, et al.
Publicado: (2020)

The effects of herbal medicine (Jujadokseo-hwan) on quality of life in patients with mild cognitive impairment: Cost-effectiveness analysis alongside randomized controlled trial
por: Lee, Ji-Eun, et al.
Publicado: (2023)

Efficacy, safety, and cost-effectiveness analysis of adjuvant herbal medicine treatment, Palmijihwang-hwan, for chronic low back pain: a study protocol for randomized, controlled, assessor-blinded, multicenter clinical trial
por: Sung, Won-Suk, et al.
Publicado: (2019)

Correction to: Effectiveness of Gyejibongnyeong-Hwan for shoulder pain: study protocol for a randomised, wait-list controlled pilot trial
por: Jang, Soobin, et al.
Publicado: (2020)

Effects of Gyejibongnyeong-hwan on dysmenorrhea caused by blood stagnation: study protocol for a randomized controlled trial
por: Park, Jeong-Su, et al.
Publicado: (2012)

Efficacy and safety of ucha-shinki-hwan on korean patients with cold hypersensitivity in the hands and feet: Study protocol clinical trial (SPIRIT Compliant)
por: Ko, Youme, et al.
Publicado: (2020)

Effects and Safety of Gyejibongnyeong-Hwan on Dysmenorrhea Caused by Blood Stagnation: A Randomized Controlled Trial
por: Park, Jeong-Su, et al.
Publicado: (2013)

Gyejibongnyeong-Hwan (Gui Zhi Fu Ling Wan) Ameliorates Human Uterine Myomas via Apoptosis
por: Lee, So Min, et al.
Publicado: (2019)

Tetragonia tetragonioides Relieves Depressive-Like Behavior through the Restoration of Glial Loss in the Prefrontal Cortex
por: Choi, Yujin, et al.
Publicado: (2021)

Safety and efficacy of Jujadokseo-hwan for memory deficit (amnesia) in mild neurocognitive disorder: A protocol for randomized, double-blind, placebo-controlled, parallel-group, multicenter clinical trial
por: Jeong, Jin-Hyung, et al.
Publicado: (2020)

Integrative Approach to Identifying System-Level Mechanisms of Chung-Sang-Bo-Ha-Hwan’s Influence on Respiratory Tract Diseases: A Network Pharmacological Analysis with Experimental Validation
por: Park, Sa-Yoon, et al.
Publicado: (2023)

Association of Dietary Behaviors with Poor Sleep Quality and Increased Risk of Obstructive Sleep Apnea in Korean Military Service Members
por: Choi, Yujin, et al.
Publicado: (2022)

Effect of herbal medicine (Huanglian-jie-du granule) for somatic symptoms and insomnia in patients with Hwa-byung: A randomized controlled trial
por: Choi, Yujin, et al.
Publicado: (2021)

Botanical Formulation HX109 Ameliorates TP-Induced Benign Prostate Hyperplasia in Rat Model and Inhibits Androgen Receptor Signaling by Upregulating Ca(2+)/CaMKKβ and ATF3 in LNCaP Cells
por: Lim, Seonung, et al.
Publicado: (2018)

Emotional freedom technique versus written exposure therapy versus waiting list for post-traumatic stress disorder: protocol for a randomised clinical MRI study
por: Choi, Yujin, et al.
Publicado: (2023)

Regulation and status of herbal medicine clinical trials in Korea: a narrative review
por: Lee, Boram, et al.
Publicado: (2021)

Effect of modified Bo-yang-Hwan-o-Tang, a polyherbal medicine on the hippocampal neuronal damage in a rat model of global ischemia
por: Oh, Tae Woo, et al.
Publicado: (2015)

Efficacy of Yukmijihwang-tang on symptoms of Alzheimer disease: A protocol for systematic review and meta-analysis
por: Lee, Seunghee, et al.
Publicado: (2021)

Redox catalysis via photoinduced electron transfer
por: Lee, Yong-Min, et al.
Publicado: (2023)

Herbal Medicine for Patients with Cognitive Impairment: An Observational Study
por: Choi, Yujin, et al.
Publicado: (2021)

The efficacy and safety of yukmijihwang-hwan (Liuweidihuang-wan) for type 2 diabetes mellitus without complications: A protocol for systematic review and meta-analysis
por: Baek, Jisoo, et al.
Publicado: (2022)

Neurocircuitry of acupuncture effect on cognitive improvement in patients with mild cognitive impairment using magnetic resonance imaging: a study protocol for a randomized controlled trial
por: Suh, Hyo-Weon, et al.
Publicado: (2019)

Moxibustion for treating knee osteoarthritis: study protocol of a multicentre randomised controlled trial
por: Lee, Seunghoon, et al.
Publicado: (2013)

Review on Diagnostic Criteria of Neurasthenia: Suggesting Pathway of Culture-bound dieases
por: Lee, Myeong Hun, et al.
Publicado: (2017)

Sirolimus Prolongs Survival after Living Donor Liver Transplantation for Hepatocellular Carcinoma Beyond Milan Criteria: A Prospective, Randomised, Open-Label, Multicentre Phase 2 Trial
por: Lee, Kwang-Woong, et al.
Publicado: (2020)

Protocol for a randomized controlled trial evaluating the effect of Hibiscus syriacus L. flower extract on sleep quality
por: Choi, Yujin, et al.
Publicado: (2023)

The clinical effects of Gyejibongnyeong-Hwan (Gui Zhi Fu Ling Wan) on patients with hyperlipidemia: A study protocol for a multicenter, double-blind, two-armed parallel, investigator-initiated, exploratory randomized controlled trial
por: Ko, Mi Mi, et al.
Publicado: (2023)

Auricular acupuncture for prehypertension and stage 1 hypertension: study protocol for a pilot multicentre randomised controlled trial
por: Kim, Joo-Hee, et al.
Publicado: (2013)

Water-Soluble Extract from Actinidia arguta (Siebold & Zucc.) Planch. ex Miq. and Perilla frutescens (L.) Britton, ACTPER, Ameliorates a Dry Skin-Induced Itch in a Mice Model and Promotes Filaggrin Expression by Activating the AhR Signaling in HaCaT Cells
por: Lee, Wonwoo, et al.
Publicado: (2019)

Mechanisms of catalytic reduction of CO(2) with heme and nonheme metal complexes
por: Fukuzumi, Shunichi, et al.
Publicado: (2018)

Efficacy and safety of Hominis placenta pharmacopuncture on mild cognitive impairment: Randomized, double blind, placebo-controlled, multi-center trial
por: Kim, Yunna, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_nngsf9mu34g61brm9fjjk9l4bf