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The inhibition of tamoxifen on UGT2B gene expression and enzyme activity in rat liver contribute to the estrogen homeostasis dysregulation

BACKGROUND: Tamoxifen treatment may induce dysregulation of estrogen homeostasis, leading to the occurrence of related adverse reactions. However, the potential mechanisms are still unclear. The purpose of the present study was to uncover whether tamoxifen treatment would act on estrogen metabolism-...

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Detalles Bibliográficos
Autores principales:	Hao, Zhixiang, Xu, Jiahao, Zhao, Han, Zhou, Wei, Liu, Zhao, He, Shiqing, Yin, Xiaoxing, Zhang, Bei, Wang, Zhongjian, Zhou, Xueyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9158366/ https://www.ncbi.nlm.nih.gov/pubmed/35642027 http://dx.doi.org/10.1186/s40360-022-00574-6

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