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Pyrroloquinoline quinone (PQQ) protects mitochondrial function of HEI-OC1 cells under premature senescence

The aim of this study was to investigate the effects of pyrroloquinoline quinone (PQQ), an oxidoreductase cofactor, on the H(2)O(2)-induced premature senescence model in HEI-OC1 auditory cells and to elucidate its mechanism of action in vitro. Cells were treated with PQQ for 1 day before H(2)O(2) (1...

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Detalles Bibliográficos
Autores principales: Gao, Ying, Kamogashira, Teru, Fujimoto, Chisato, Iwasaki, Shinichi, Yamasoba, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9158787/
https://www.ncbi.nlm.nih.gov/pubmed/35927260
http://dx.doi.org/10.1038/s41514-022-00083-0