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An economical approach for peptide synthesis via regioselective C–N bond cleavage of lactams

An economical, solvent-free, and metal-free method for peptide synthesis via C–N bond cleavage using lactams has been developed. The method not only eliminates the need for condensation agents and their auxiliaries, which are essential for conventional peptide synthesis, but also exhibits high atom...

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Detalles Bibliográficos
Autores principales: Muramatsu, Wataru, Yamamoto, Hisashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159104/
https://www.ncbi.nlm.nih.gov/pubmed/35733900
http://dx.doi.org/10.1039/d2sc01466a