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Effects of Intranasal and Oral Bordetella bronchiseptica Vaccination on the Behavioral and Olfactory Capabilities of Detection Dogs

The bacterium Bordetella bronchiseptica is responsible for serious respiratory disease in dogs, most often associated with ‘kennel cough’ (canine infectious tracheobronchitis). It is recommended that dogs are vaccinated against the bacterium every 6–12 months, either by oral or intranasal administra...

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Autores principales: Collins, Amanda, Bear, Rachel A., Mallikarjun, Amritha, Kane, Sarah A., Essler, Jennifer L., Kaynaroglu, Patricia, Feuer, Rebecca, Smith, Jordan G., Otto, Cynthia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159271/
https://www.ncbi.nlm.nih.gov/pubmed/35664843
http://dx.doi.org/10.3389/fvets.2022.882424
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author Collins, Amanda
Bear, Rachel A.
Mallikarjun, Amritha
Kane, Sarah A.
Essler, Jennifer L.
Kaynaroglu, Patricia
Feuer, Rebecca
Smith, Jordan G.
Otto, Cynthia M.
author_facet Collins, Amanda
Bear, Rachel A.
Mallikarjun, Amritha
Kane, Sarah A.
Essler, Jennifer L.
Kaynaroglu, Patricia
Feuer, Rebecca
Smith, Jordan G.
Otto, Cynthia M.
author_sort Collins, Amanda
collection PubMed
description The bacterium Bordetella bronchiseptica is responsible for serious respiratory disease in dogs, most often associated with ‘kennel cough’ (canine infectious tracheobronchitis). It is recommended that dogs are vaccinated against the bacterium every 6–12 months, either by oral or intranasal administration. Any impairment of dogs' olfactory capabilities due to medical treatments may impact their efficiency and accuracy in their jobs. This study examined (1) the effect of intranasal and oral vaccines on the olfactory capabilities of detection dogs; as well as (1) effects of the vaccines on canine behavior. Dogs that were vaccinated initially with the oral and 28 days later with intranasal B. bronchiseptica were generally slower to find the target odor than the dogs that were assigned intranasal then oral vaccine. This result prompted a second between-subjects study to further investigate any impact of intranasal administration of the B. bronchiseptica vaccine on the olfactory capabilities of dogs. The intranasal vaccine was of particular interest due to its prevalent use and potential for nasal inflammation leading to decreased olfactory capabilities. Neither odor threshold nor time spent searching for odor were affected by the intranasal vaccine. Behavioral analyses showed that behaviors associated with the dogs' positive and negative motivation affected their time spent finding the target odor; this suggests that behavior should be considered in future studies of olfactory performance.
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spelling pubmed-91592712022-06-02 Effects of Intranasal and Oral Bordetella bronchiseptica Vaccination on the Behavioral and Olfactory Capabilities of Detection Dogs Collins, Amanda Bear, Rachel A. Mallikarjun, Amritha Kane, Sarah A. Essler, Jennifer L. Kaynaroglu, Patricia Feuer, Rebecca Smith, Jordan G. Otto, Cynthia M. Front Vet Sci Veterinary Science The bacterium Bordetella bronchiseptica is responsible for serious respiratory disease in dogs, most often associated with ‘kennel cough’ (canine infectious tracheobronchitis). It is recommended that dogs are vaccinated against the bacterium every 6–12 months, either by oral or intranasal administration. Any impairment of dogs' olfactory capabilities due to medical treatments may impact their efficiency and accuracy in their jobs. This study examined (1) the effect of intranasal and oral vaccines on the olfactory capabilities of detection dogs; as well as (1) effects of the vaccines on canine behavior. Dogs that were vaccinated initially with the oral and 28 days later with intranasal B. bronchiseptica were generally slower to find the target odor than the dogs that were assigned intranasal then oral vaccine. This result prompted a second between-subjects study to further investigate any impact of intranasal administration of the B. bronchiseptica vaccine on the olfactory capabilities of dogs. The intranasal vaccine was of particular interest due to its prevalent use and potential for nasal inflammation leading to decreased olfactory capabilities. Neither odor threshold nor time spent searching for odor were affected by the intranasal vaccine. Behavioral analyses showed that behaviors associated with the dogs' positive and negative motivation affected their time spent finding the target odor; this suggests that behavior should be considered in future studies of olfactory performance. Frontiers Media S.A. 2022-05-18 /pmc/articles/PMC9159271/ /pubmed/35664843 http://dx.doi.org/10.3389/fvets.2022.882424 Text en Copyright © 2022 Collins, Bear, Mallikarjun, Kane, Essler, Kaynaroglu, Feuer, Smith and Otto. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Veterinary Science
Collins, Amanda
Bear, Rachel A.
Mallikarjun, Amritha
Kane, Sarah A.
Essler, Jennifer L.
Kaynaroglu, Patricia
Feuer, Rebecca
Smith, Jordan G.
Otto, Cynthia M.
Effects of Intranasal and Oral Bordetella bronchiseptica Vaccination on the Behavioral and Olfactory Capabilities of Detection Dogs
title Effects of Intranasal and Oral Bordetella bronchiseptica Vaccination on the Behavioral and Olfactory Capabilities of Detection Dogs
title_full Effects of Intranasal and Oral Bordetella bronchiseptica Vaccination on the Behavioral and Olfactory Capabilities of Detection Dogs
title_fullStr Effects of Intranasal and Oral Bordetella bronchiseptica Vaccination on the Behavioral and Olfactory Capabilities of Detection Dogs
title_full_unstemmed Effects of Intranasal and Oral Bordetella bronchiseptica Vaccination on the Behavioral and Olfactory Capabilities of Detection Dogs
title_short Effects of Intranasal and Oral Bordetella bronchiseptica Vaccination on the Behavioral and Olfactory Capabilities of Detection Dogs
title_sort effects of intranasal and oral bordetella bronchiseptica vaccination on the behavioral and olfactory capabilities of detection dogs
topic Veterinary Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159271/
https://www.ncbi.nlm.nih.gov/pubmed/35664843
http://dx.doi.org/10.3389/fvets.2022.882424
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