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Engineering Human Circulating Monocytes/Macrophages by Systemic Deliverable Gene Editing

Delivery of plasmid DNA to transfect human primary macrophages is extremely difficult, especially for genetic engineering. Engineering macrophages is imperative for the treatment of many diseases including infectious diseases, cancer, neurological diseases, and aging. Unfortunately, plasmid does not...

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Detalles Bibliográficos
Autores principales: Lee, So Yoon, Fierro, Javier, Dipasquale, Jake, Bastian, Anthony, Tran, An M., Hong, Deawoo, Chin, Brandon, Nguyen-Lee, Paul J., Mazal, Sarah, Espinal, Jamil, Thomas, Tima, Dou, Huanyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159279/
https://www.ncbi.nlm.nih.gov/pubmed/35663976
http://dx.doi.org/10.3389/fimmu.2022.754557