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Structural basis of human LRG1 recognition by Magacizumab, a humanized monoclonal antibody with therapeutic potential

The formation of new dysfunctional blood vessels is a crucial stage in the development of various conditions such as macular degeneration, diabetes, cardiovascular disease, neurological disease and inflammatory disorders, as well as during tumor growth, eventually contributing to metastasis. An impo...

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Detalles Bibliográficos
Autores principales: Gutiérrez-Fernández, Javier, Javaid, Faiza, De Rossi, Giulia, Chudasama, Vijay, Greenwood, John, Moss, Stephen E., Luecke, Hartmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159282/
https://www.ncbi.nlm.nih.gov/pubmed/35647920
http://dx.doi.org/10.1107/S2059798322004132