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Structural basis of human LRG1 recognition by Magacizumab, a humanized monoclonal antibody with therapeutic potential
The formation of new dysfunctional blood vessels is a crucial stage in the development of various conditions such as macular degeneration, diabetes, cardiovascular disease, neurological disease and inflammatory disorders, as well as during tumor growth, eventually contributing to metastasis. An impo...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159282/ https://www.ncbi.nlm.nih.gov/pubmed/35647920 http://dx.doi.org/10.1107/S2059798322004132 |