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Failed Eradication Therapy of New-Onset Pseudomonas aeruginosa Infections in Children With Cystic Fibrosis Is Associated With Bacterial Resistance to Neutrophil Functions

BACKGROUND: Antibiotics, such as inhaled tobramycin, are used to eradicate new-onset Pseudomonas aeruginosa (PA) infections in patients with cystic fibrosis (CF) but frequently fail due to reasons poorly understood. We hypothesized that PA isolates’ resistance to neutrophil antibacterial functions w...

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Detalles Bibliográficos
Autores principales: Kwong, Kelly, Benedetti, Andrea, Yau, Yvonne, Waters, Valerie, Nguyen, Dao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159338/
https://www.ncbi.nlm.nih.gov/pubmed/33606875
http://dx.doi.org/10.1093/infdis/jiab102