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Inhibitory Effects of Macelignan on Tau Phosphorylation and Aβ Aggregation in the Cell Model of Alzheimer's Disease

Alzheimer's disease (AD) is a neurodegenerative disorder mainly affecting old population. In this study, two Tau overexpressing cell lines (SH-SY5Y/Tau and HEK293/Tau), N2a/SweAPP cell line, and 3× Transgene (APPswe/PS1M146V/TauP301L) mouse primary nerve cell lines were used as AD models to stu...

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Detalles Bibliográficos
Autores principales:	Gu, Liang, Cai, Nan, Li, Meiting, Bi, Decheng, Yao, Lijun, Fang, Weishan, Wu, Yan, Hu, Zhangli, Liu, Qiong, Lin, Zhijian, Lu, Jun, Xu, Xu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Nutrition
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159362/ https://www.ncbi.nlm.nih.gov/pubmed/35662922 http://dx.doi.org/10.3389/fnut.2022.892558

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