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Are anaplastic lymphoma kinase (ALK) and O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation driver biomarkers of pulmonary neuroendocrine tumors (NETs) and carcinomas (NECs)?

Background: Novel targets in neuroendocrine tumors (NETs) and neuroendocrine carcinomas (NECs) are needed to improve outcome. The presence of O6-Methylguanine-DNA methyltransferase (MGMT) promoter methylation in NETs and NECs may act as a predictive marker for response on treatment with temozolomide...

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Detalles Bibliográficos
Autores principales:	Hiddinga, Birgitta, Zwaenepoel, Karen, Janssens, Annelies, Van Meerbeeck, Jan, Pauwels, Patrick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159705/ https://www.ncbi.nlm.nih.gov/pubmed/35677534 http://dx.doi.org/10.18632/oncotarget.28240

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