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Two Distinct Neural Mechanisms Underlying Acupuncture Analgesia

Acupuncture analgesia is a traditional treatment with a long history, although it lacks scientific evidence. It is reportedly associated with the central nervous system, including various brain regions, from the cortices to the brain stem. However, it remains unclear whether the distributed regions...

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Autores principales: Kato, Yasutaka, Yachi, Kazuhiro, Hoshi, Hideyuki, Okada, Toyoji, Shigihara, Yoshihito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159800/
https://www.ncbi.nlm.nih.gov/pubmed/35663250
http://dx.doi.org/10.3389/fpain.2022.869884
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author Kato, Yasutaka
Yachi, Kazuhiro
Hoshi, Hideyuki
Okada, Toyoji
Shigihara, Yoshihito
author_facet Kato, Yasutaka
Yachi, Kazuhiro
Hoshi, Hideyuki
Okada, Toyoji
Shigihara, Yoshihito
author_sort Kato, Yasutaka
collection PubMed
description Acupuncture analgesia is a traditional treatment with a long history, although it lacks scientific evidence. It is reportedly associated with the central nervous system, including various brain regions, from the cortices to the brain stem. However, it remains unclear whether the distributed regions behave as a single unit or consist of multiple sub-units playing different roles. Magnetoencephalography is a neuroimaging technique that can measure the oscillatory frequency of neural signals and brain regions. The frequency band of neural signals allows further understanding of the characteristics of the acupuncture-related neural systems. This study measured resting-state brain activity using magnetoencephalography in 21 individuals with chronic pain before and after acupuncture treatment. The subjective level of pain was assessed using a visual analog scale, and brain activity was compared to identify the brain regions and the frequencies associated with acupuncture analgesia. Here, we categorized the changes in resting-state brain activity into two groups: low-frequency oscillatory activity (<3 Hz) in the left middle occipital and right superior partial lobule and high-frequency oscillatory activity (81–120 Hz) on both sides of the prefrontal, primary sensory, and right fusiform gyri. These findings suggest that acupuncture analgesia influences two or more sub-units of the neural systems, which helps us understand the neural mechanisms underlying acupuncture analgesia.
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spelling pubmed-91598002022-06-02 Two Distinct Neural Mechanisms Underlying Acupuncture Analgesia Kato, Yasutaka Yachi, Kazuhiro Hoshi, Hideyuki Okada, Toyoji Shigihara, Yoshihito Front Pain Res (Lausanne) Pain Research Acupuncture analgesia is a traditional treatment with a long history, although it lacks scientific evidence. It is reportedly associated with the central nervous system, including various brain regions, from the cortices to the brain stem. However, it remains unclear whether the distributed regions behave as a single unit or consist of multiple sub-units playing different roles. Magnetoencephalography is a neuroimaging technique that can measure the oscillatory frequency of neural signals and brain regions. The frequency band of neural signals allows further understanding of the characteristics of the acupuncture-related neural systems. This study measured resting-state brain activity using magnetoencephalography in 21 individuals with chronic pain before and after acupuncture treatment. The subjective level of pain was assessed using a visual analog scale, and brain activity was compared to identify the brain regions and the frequencies associated with acupuncture analgesia. Here, we categorized the changes in resting-state brain activity into two groups: low-frequency oscillatory activity (<3 Hz) in the left middle occipital and right superior partial lobule and high-frequency oscillatory activity (81–120 Hz) on both sides of the prefrontal, primary sensory, and right fusiform gyri. These findings suggest that acupuncture analgesia influences two or more sub-units of the neural systems, which helps us understand the neural mechanisms underlying acupuncture analgesia. Frontiers Media S.A. 2022-05-18 /pmc/articles/PMC9159800/ /pubmed/35663250 http://dx.doi.org/10.3389/fpain.2022.869884 Text en Copyright © 2022 Kato, Yachi, Hoshi, Okada and Shigihara. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pain Research
Kato, Yasutaka
Yachi, Kazuhiro
Hoshi, Hideyuki
Okada, Toyoji
Shigihara, Yoshihito
Two Distinct Neural Mechanisms Underlying Acupuncture Analgesia
title Two Distinct Neural Mechanisms Underlying Acupuncture Analgesia
title_full Two Distinct Neural Mechanisms Underlying Acupuncture Analgesia
title_fullStr Two Distinct Neural Mechanisms Underlying Acupuncture Analgesia
title_full_unstemmed Two Distinct Neural Mechanisms Underlying Acupuncture Analgesia
title_short Two Distinct Neural Mechanisms Underlying Acupuncture Analgesia
title_sort two distinct neural mechanisms underlying acupuncture analgesia
topic Pain Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159800/
https://www.ncbi.nlm.nih.gov/pubmed/35663250
http://dx.doi.org/10.3389/fpain.2022.869884
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