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Genetic and Epigenetic Mechanisms Deregulate the CRL2(pVHL) Complex in Hepatocellular Carcinoma

Dysregulation of ubiquitin-proteasome pathway genes through copy number alteration, promoter hypomethylation, and miRNA deregulation is involved in cancer development and progression. Further characterizing alterations in these genes may uncover novel drug targets across a range of diseases in which...

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Detalles Bibliográficos
Autores principales:	Minatel, Brenda C., Cohn, David E., Pewarchuk, Michelle E., Barros-Filho, Mateus C., Sage, Adam P., Stewart, Greg L., Marshall, Erin A., Telkar, Nikita, Martinez, Victor D., Reis, Patricia P., Robinson, Wendy P., Lam, Wan L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159809/ https://www.ncbi.nlm.nih.gov/pubmed/35664333 http://dx.doi.org/10.3389/fgene.2022.910221

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