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Chlorogenic Acid Prevents Microglia-Induced Neuronal Apoptosis and Oxidative Stress under Hypoxia-Ischemia Environment by Regulating the MIR497HG/miR-29b-3p/SIRT1 Axis

BACKGROUND: Chlorogenic acid (CGA) is a polyphenolic compound with antioxidant and anti-inflammatory properties. CGA has been shown to improve neuroinflammation. This study is aimed at elucidating the exact mechanism by which CGA reduces neuroinflammation. METHODS: Oxygen and glucose deprivation (OG...

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Detalles Bibliográficos
Autores principales: Fan, Yong, Li, Yongkun, Yang, Yongkai, Lin, Kunzhe, Lin, Qingqiang, Luo, Shenghui, Zhou, Xiaohui, Lin, Qun, Zhang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159818/
https://www.ncbi.nlm.nih.gov/pubmed/35664431
http://dx.doi.org/10.1155/2022/1194742