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A2A Receptor Contributes to Tumor Progression in P2X7 Null Mice
ATP and adenosine are key constituents of the tumor niche where they exert opposite and complementary roles. ATP can be released in response to cell damage or actively released by tumor cells and subsequently degraded into adenosine, which accumulates within the tumor microenvironment. Notably, whil...
Autores principales: | De Marchi, Elena, Pegoraro, Anna, Turiello, Roberta, Di Virgilio, Francesco, Morello, Silvana, Adinolfi, Elena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159855/ https://www.ncbi.nlm.nih.gov/pubmed/35663396 http://dx.doi.org/10.3389/fcell.2022.876510 |
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