Immunosuppression broadens evolutionary pathways to drug resistance and treatment failure during Acinetobacter baumannii pneumonia in mice

Acinetobacter baumannii is increasingly refractory to antibiotic treatment in healthcare settings. As is true of most human pathogens, the genetic path to antimicrobial resistance (AMR) and the role that the immune system plays in modulating AMR during disease are poorly understood. Here we reproduc...

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Detalles Bibliográficos
Autores principales: Huo, Wenwen, Busch, Lindsay M., Hernandez-Bird, Juan, Hamami, Efrat, Marshall, Christopher W., Geisinger, Edward, Cooper, Vaughn S., van Opijnen, Tim, Rosch, Jason W., Isberg, Ralph R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159950/
https://www.ncbi.nlm.nih.gov/pubmed/35618774
http://dx.doi.org/10.1038/s41564-022-01126-8

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