Identification of shared and disease-specific host gene–microbiome associations across human diseases using multi-omic integration

While gut microbiome and host gene regulation independently contribute to gastrointestinal disorders, it is unclear how the two may interact to influence host pathophysiology. Here we developed a machine learning-based framework to jointly analyse paired host transcriptomic (n = 208) and gut microbi...

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Detalles Bibliográficos
Autores principales: Priya, Sambhawa, Burns, Michael B., Ward, Tonya, Mars, Ruben A. T., Adamowicz, Beth, Lock, Eric F., Kashyap, Purna C., Knights, Dan, Blekhman, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159953/
https://www.ncbi.nlm.nih.gov/pubmed/35577971
http://dx.doi.org/10.1038/s41564-022-01121-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159953/
https://www.ncbi.nlm.nih.gov/pubmed/35577971
http://dx.doi.org/10.1038/s41564-022-01121-z

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