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Mechanical forces couple bone matrix mineralization with inhibition of angiogenesis to limit adolescent bone growth
Bone growth requires a specialised, highly angiogenic blood vessel subtype, so-called type H vessels, which pave the way for osteoblasts surrounding these vessels. At the end of adolescence, type H vessels differentiate into quiescent type L endothelium lacking the capacity to promote bone growth. U...
Autores principales: | Dzamukova, Maria, Brunner, Tobias M., Miotla-Zarebska, Jadwiga, Heinrich, Frederik, Brylka, Laura, Mashreghi, Mir-Farzin, Kusumbe, Anjali, Kühn, Ralf, Schinke, Thorsten, Vincent, Tonia L., Löhning, Max |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160028/ https://www.ncbi.nlm.nih.gov/pubmed/35650194 http://dx.doi.org/10.1038/s41467-022-30618-8 |
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